IMO it should not matter what marking system you use with TMM!
The idea is one man on one man throughout the match to prevent the opposing player getting on the ball or playing their game
If you are playing zonal and the target player enters another of your players zones (not your TMM players zone) then both players should mark and challenge the opposing player!
If you are playing man marking then the TMM player should mark as well as your player with the opposite number of the target man (if the TMM player is not the opposite number)!
This strategy should not improve your team efficiency but, when used right, should worsen the oppositions efficiency
Hence, if the opposition is using target man and playing a lone striker as the target (5-4-1 for example).. big thumbs up!!!
If they play the same strategy with three strikers (4-3-3 for example) you are in trouble
You should use a dmc with high marking, tackling, acceleration and pace ideally... or your next best defender IMO
hope this helps!!